70-kDa Ribosomal Protein S6 Kinases

A family of ribosomal protein S6 kinases that are considered the major physiological kinases for RIBOSOMAL PROTEIN S6. Unlike RIBOSOMAL PROTEIN S6 KINASES, 90KDa the proteins in this family are sensitive to the inhibitory effects of RAPAMYCIN and contain a single kinase domain. They are referred to as 70kDa proteins, however ALTERNATIVE SPLICING of mRNAs for proteins in this class also results in 85kDa variants being formed.

Also Known As:

Ribosomal Protein S6 Kinases, 70 kDa; p70s6k; Ribosomal Protein S6 Kinases, 70-kDa; S6 Kinase, p70; p70 S6 Kinase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        Ribosomal Protein S6 Kinases: 524
        70-kDa Ribosomal Protein S6 Kinases: 925
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - Ribosomal Protein S6 Kinases: 524
        70-kDa Ribosomal Protein S6 Kinases: 925

Osamu Omori Selected Research

Osamu Omori Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure